Place ground beef in a bowl and break up the meat slightly. Add the taco seasoning, mayonnaise and bread crumbs and gently mix until ingredients are blended. Shape in burger patties. 6 - 8 depending on the size. Grill or broil until done, about 5 minutes per side.
For the aioli. In a small bowl, mix the mayonnaise and the salsa with a fork until well blended.
To build the burger: place lettuce on the bottom bun. Top with a hamburger patty, a good dollop of the salsa aioli, a slice of tomato and a couple slices of sweet onion.